Grandma Chase is the mother of Randolph, Natalie and Frederick Chase, grandmother of Annabeth, Magnus, Aubrey, Bobby, Emma and Matthew Chase, and the wife of Grandpa Chase.
Grandma Chase married a man and had two sons and a daughter with him. She and her family lived in a brownstone mansion in Boston. She died before meeting her grandchildren.
Magnus finds a picture of her and her husband in the library of the family mansion.