Through the King Zeus, Leto is the mother of Apollo and Artemis. When she was pregant with the twins, she was pursued relentlessly by the goddess Hera, who drove her from land to land preventing her from finding a place to rest and give birth. The floating island of Delos eventually provided her with refuge. Later when she was later traveling to Delphi, the giant Tityos attempted to abduct her, but Apollo intervened and slew him with arrows.
Latona is Leto's Roman counterpart. As Latona, she becomes more disciplined, warlike, and militaristic. In Roman mythology, she is the titaness of motherhood and modesty.
Her son Apollo mentions her frequently throughout the book.
- Leto makes her only appearance in Percy Jackson's Greek Gods, though she is mentioned in The House of Hades.