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Orthus is a two headed monster dog and the brother of Cerberus. He appears in The Battle of the Labyrinth under the ownership of Eurytion. He also appears in Percy Jackson's Greek Heroes where he is killed by Hercules

Percy Jackson and the Olympians

The Battle of the Labyrinth

Orthus had reformed along with Geryon. Although his official master is Geryon, he tends to listen more to Eurytion as he takes care of him, unlike Geryon. Similar to the ancient myths (Hercules), Percy Jackson, came to the ranch and killed Geryon, but unlike Hercules, he spared Orthus as he did not participate in defending his master because Eurytion had told him to stay back during the fight between Percy and Geryon.

Geryon

Geryon, Orthus' official owner.

Monsters
Species: Centaur | Cyclopes | Dragon | Drakon | Empousai | Fire-Breathing Horse | Giants | Gorgons | Harpies | Hyperborean Giants | Ichthyocentaur | Katoblepones | Laistrygonian Giants | Lycanthrope | Merpeople | Nikai | Nymphs | Pegasus | Satyrs | Stymphalian Birds | Telekhines | Blemmyae | Basilisks | Sirens | Gemini | Scythian Dracanae | Ghoul | Hekatonkheires | Myrmekes | Unicorns | Hippalektryons | Arai | Gegeines | Karpoi | Makhai | Keres | Hippocampi | Venti | Yales
Friendly Monsters: Argus | Blackjack | Briares | Cottus | Gyges | Chiron | Don | Ella | Festus | Gleeson Hedge | Gray |Grover Underwood | Lysas | Rainbow | Mellie | Mrs. O'Leary | Ophiotaurus | Peleus | Porkpie | Guido | Scipio | Tyson | Tempest | Sssssarah | Peaches
Enemy Monsters: Agrius and Oreius | Arachne | Charybdis and Scylla | Chimera | Chrysaor | Clazmonian Sow | Colchis Bulls | Echidna | Euryale | Geryon | Joe Bob | Kampê | | Nanette | Manticore | Medusa | Minotaur | Nemean Lion | Polyphemus | Sphinx | Lamia | Medusa | Euryale | Stheno | Typhon | Python | Kekrops | Cacus | Trojan Sea Monster | Ladon | Antaeus
Neutral Monsters: Carnivorous Sheep | Cerberus | Erymanthian Boar | Gray Sisters | Furies | Flesh-Eating Horse | Gryphon | Skolopendra | Sybaris | Orthus